Hematology & Transfusion Medicine

A blog dedicated to Hematology & Transfusion Medicine serves as a valuable resource for healthcare professionals, researchers, students, and even patients seeking information on blood-related disorders and transfusion practices.

Hematology & Transfusion Medicine

Stop the Irrational Use of Antibiotics: An Open Letter to the Community

          Dear Citizens & Community, I write to you with grave concern about a growing threat to public health that is silently but steadily affecting our families, our neighbours, and our future generations. The misuse and overuse of antibiotics by certain medical assistants—who are not qualified physicians—is not just a matter

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Hematology & Transfusion Medicine

Case Report: IgM-Kappa Restricted AL Amyloidosis with Renal Involvement

Case Report: IgM-Kappa Restricted AL Amyloidosis with Renal Involvement   AL amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of misfolded light chains in various organs. We report a case of a 38-year-old male with recurrent bilateral leg swelling and proteinuria, diagnosed with renal AL amyloidosis with IgM-kappa restriction. The diagnosis was

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Hematology & Transfusion Medicine

Case Report: A 40-Year-Old Male with Generalized Lymphadenopathy Diagnosed with Hodgkin Lymphoma

IHC findings of classical Hodgkin’s Lymphoma Case Report: A 40-Year-Old Male with Generalized Lymphadenopathy Diagnosed with Hodgkin Lymphoma Abstract Hodgkin lymphoma (HL) is a malignant disorder of the lymphatic system characterized by the presence of Reed-Sternberg cells. Here, we report a case of a 40-year-old male presenting with generalized lymphadenopathy. Histopathological examination and immunohistochemistry confirmed

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Hematology & Transfusion Medicine

Case Report: Hemoglobin H Disease with Compound Heterozygous -3.7 Deletion and Hb Constant Spring Mutation

Abstract Hemoglobin H (Hb H) disease is a moderate to severe form of alpha thalassemia resulting from impaired alpha globin production. We report a case of a patient with Hb H disease caused by compound heterozygosity for a deletional -3.7 mutation and a Hb Constant Spring (Hb CS) mutation. The patient presented with chronic anemia

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Hematology & Transfusion Medicine

Benefits of Patient Access Program (PAP) and Compassionate Access Program (CAP) for Treatment of Hematological Malignancy: Experience from a Tertiary Hospital

        Abstract Haematological malignancies are life-threatening disorders requiring specialized care, including costly medications and therapies. In resource-limited settings, the financial burden often limits access to optimal treatment. Patient Access Programs (PAP) and Compassionate Access Programs (CAP) have been instrumental in bridging this gap, ensuring equitable treatment access. This article explores the benefits

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Hematology & Transfusion Medicine

Social and Financial Barriers to Optimum TKI Treatment in Patients with Chronic Myeloid Leukaemia: A Knowledge-Attitudes-Practices Study from a Tertiary Hospital of Bangladesh

             Abstract Chronic Myeloid Leukemia (CML) is a haematologic malignancy effectively managed with tyrosine kinase inhibitors (TKIs). However, social and financial barriers often limit optimal treatment, especially in low-resource settings like Bangladesh. This study aimed to evaluate the knowledge, attitudes, and practices (KAP) of CML patients regarding TKI therapy and

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Hematology & Transfusion Medicine

Addressing Stigma in Haemophilia Management: Insights from Two Tertiary Hospitals in a Low-Income Country

Background and Aims: Haemophilia is a rare bleeding disorder that poses significant health and social challenges, especially in low-income countries where stigma and misconceptions hinder effective management. Stigma leads to social isolation, discrimination, and psychological distress among patients and caregivers, while also impacting healthcare access and treatment adherence. This study aims to explore the stigma

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Hematology & Transfusion Medicine

A Pragmatic Approach to Manage Long-Term Adverse Effects in CML Treatment

A Pragmatic Approach to Manage Long-Term Adverse Effects in CML Treatment Abstract Introduction and Objectives: Chronic Myeloid Leukemia (CML) is a hematologic malignancy effectively managed with tyrosine kinase inhibitors (TKIs). Despite their success in prolonging survival, TKIs are associated with long-term adverse effects that can significantly impact patient quality of life and treatment adherence. This

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Hematology & Transfusion Medicine

A Compound Heterozygote case of Transfusion dependent Thalassaemia (TDT)

    Abstract Hemoglobin H (Hb H) disease is a moderate to severe form of alpha thalassemia resulting from impaired alpha globin production. We report a case of a patient with Hb H disease caused by compound heterozygosity for a deletional -3.7 mutation and a Hb Constant Spring (Hb CS) mutation. The patient presented with

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